KEGG   REACTION: R06468
Entry
R06468                      Reaction                               
Definition
6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2b'' aglycone + NADPH + Oxygen <=> 5-Oxoavermectin ''2b'' aglycone + NADP+ + H2O
Equation
Comment
cytochrome P450 hydroxylase,AveE
Reaction class
RC00001  C00005_C00006
RC01527  C11953_C11954
Enzyme
1.14.-.-
Pathway
rn00522  Biosynthesis of 12-, 14- and 16-membered macrolides
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.-  Acting on paired donors, with incorporation or reduction of molecular oxygen
    1.14.-.-
     R06468  6,8a-Seco-6,8a-deoxy-5-oxoavermectin ''2b'' aglycone + NADPH + Oxygen <=> 5-Oxoavermectin ''2b'' aglycone + NADP+ + H2O
Orthology
K14372  cytochrome P450 hydroxylase [EC:1.14.-.-]

DBGET integrated database retrieval system